Episodic Ataxia Ataxia Episódica
They had never seen this disorder before, and they too suggested I see a psychiatrist.
I have Familial Episodic Ataxia (type 2) the generic name given to a rare syndrome which causes nausea, dysarthria, dysmetria, ataxia, etc. To those who do not know me, I appear completely normal between attacks. But those who know me also know that life can be more than just an everyday struggle. They can tell the signs when I am trying to fight off the attacks. One day, I may be fine, but the next day, I may not be able to walk at all or do the most fundamental things like hold a pencil in my hand.
Ataxia is rare, and Episodic Ataxia is one of the rarest in the family of Ataxias. Aside from my family, (I have 13 brothers and sisters), I have found only a handful of families that have this type of Ataxia. Seven other brothers and sisters of my family also have the gene, including an uncle and some of his children. I have been the fortunate one to have it the worse in my family.
My story begins at the age of 13, during my first year of high school. We had six class periods a day. I recall that after my physical education class, I always began to feel dizzy and sick. The class following physical education was sixth period English. At the time I didn't understand why, but I always spent the class with my head lying on the desk. There were many days I had to excuse myself from class and go to the nurse's office.
I had no idea what was happening. I began to get sick frequently. When I became sick, my eye pupils shook uncontrollably, (the doctors call this nystagmus), I became dizzy, I had difficulty in walking (I walked as if I were drunk). Nausea followed the dizziness, and it usually took three to four hours before it subsided. One time in the nurse’s office, during one of my episodes, while I was lying down, one of the nurses approached me. She sat down beside me and asked, "Do you smoke marijuana?". I was startled by her words. My reply was an unequivocal, "no". I had no idea what was happening to me, but I was surprised by the reaction of this nurse.
My parents took me to Kaiser Medical Center several times. The doctors ran several tests to find out what was wrong, but nothing showed up. I found out years later one of the doctors suggested to my father, I was taking drugs. I had ordered my records from Kaiser Medical Center many years after my father took me to see the physician. While I was ruffling through the pages, I found a document which had a conversation between the neurologist and my father. The neurologist asked my father, "Has your son taken any hallucinogens? and my father replied, "Not to my knowledge, but he has been a little rebellious lately." So now my father believed I was on drugs.
What is episodic Ataxia – How to control it
A person affected by episodic Ataxia experiences periods of imbalance, lack of coordination and confusing speech. Resort to the experience of proficient escorts to know the different types of this disorder and how to identify them.
Symptoms attributed to episodic Ataxia
Episodic Ataxia constitutes a group of diseases that affect the central nervous system causing motor imbalance and a deficient coordination. The person affected by this kind of illness experiences many symptoms during each episode. As your clever Los Angeles escort will explain you, such manifestations include nausea, dizziness, migraines, vomiting, double or blurred vision, tinnitus and dyslexia.
Additional signs like hemiplegia, muscle weakness and seizures might be experienced by the patient during an episode.
These diseases can manifest themselves at any time, from childhood to adulthood. Smart ladies like those from the Escort Directory will explain you that they can be triggered by the intake of caffeine, alcohol and specific drugs. They can also be activated by emotional stress, environmental factors or certain medical conditions. Episodes frequency is variable and ranges from several per day to one or two per year.
Physicians have identified at least 7 types of episodic Ataxia. They are differentiated by a particular set of signs manifested by the patient. Such characteristics include the duration of attacks, the age of onset, and the genetic cause.
There are several genes involved in the occurrence of these processes. Your intelligent Los Angeles escort will tell you that the SLC1A3 is one of them. Such DNA regions encode proteins that participate in the transportation of ions through the membranes of neurons. This event is necessary for the transmission of communication signals between brain cells and other areas of nervous system.
Characteristics of the most important types of this disease
Type 1 is caused by the alteration of KCNA1 gene. It belongs to a group responsible for the construction of potassium channels which are fundamental to allow the communication between cells by means of the transmission of electrical signals. Acquainted escorts will inform you that this DNA locus encodes the alpha subunit of the mentioned conduit known as Kv1.1.
Reports have confirmed the existence of at least 19 mutations of the mentioned gene on people affected by type 1. Most of these alterations change the amino acids of the Kv1.1 alpha subunit. Such situation decreases the potassium flow between neurons disrupting their communication.
Type 2 of episodic Ataxia is produced by the alteration of CACNA1A gene. It belongs to a group that encodes the structure of calcium channels. Ions transported through such conduits participate in various cellular functions that include communication between them and neuron survival as your expert Los Angeles escort will explain you.
The referred gene encodes the alpha 1 subunit known as Cav2.1 responsible for creating a passage for the flow of calcium. Reports have confirmed around 49 mutations of this DNA locus.
Mutations of CACNA1A gene prevent the calcium channels from reaching the cell membrane. Skillful escorts will tell you that such situation interrupts the release of neurotransmitters in the brain. According to many physicians, oral acetazolemide has helped some patients in the cessation of seizures and symptoms. However, in some other cases this medicine did not provide effective results.